2) World of Warcraft (Activision)
This beast was loosed on the world with its first installment, Warcraft: Orcs and Humans in 1994. Now in 2011, there are who the hell knows how many different installments of this franchise and approximately 567 billion people play World of Warcraft every day. It has grown to such unbelievable proportions that many feel that WOW is the SkyTel that James Cameron was warning us about. See for yourself.